HIGH-TECH LABCOURSES
HIGH-TECH
LABCOURSES
In vivo, ex vivo mechanical tests on soft tissue
Mechanical testing of biological tissues plays a key role in biomechanics research. The tissue mechanical properties (elasticity, stiffness, strength, viscoelasticity) may be then extracted from these data. These mechanical properties are essential to feed numerical models of the human body, whether used in medical simulation, medical device design, or fundamental research.
By reproducing physiological or pathological conditions, such tests provide a better understanding of deformation and failure mechanisms. They therefore help improve the accuracy of models, and consequently the reliability of both clinical and industrial applications.
PREREQUISITE
Participants must be able to understand the principles of mechanical testing and of parameter identification.
DESCRIPTION
Suction tests on living tissue using the V-lastic suction principle (2 hrs session)
In this module, a portable suction device (VLASTIC) will be presented and tested on volunteer’s skin. This experimental session will to provide insight about the challenges to perform in-vivo measurements. Mechanical elasticity parameters (Young moduli) of bilayer materials models will then be extracted from experimental curves obtained with different suction diameters. The extraction sensitivity to noise and hypotheses will be highlighted during this inverse identification process.
Uniaxial tensile testing on ex vivo tissues and modelling (2 hrs session)
In this module, uniaxial tensile tests will be performed. The challenges involved in setting up these tests will be compared to uniaxial tensile tests on industrial materials. An approach to characterisation using a hyperelastic model will be proposed if time permits.
LOCATION
Laboratoire TIMC - 6 chemin Saint-Ferjus
38 700 La Tronche